Lead Compound Identification Chemistry Assignment Help
Lead Compound Identification
For the synthesis and selection of biologically relevant compounds a large number of compounds are tested for their ability to effect the action of target proteins.
Compounds are mainly identified using random screening or through design approaches. For a compound to be identified as potential drug it should fulfill the following criteria:
b) Physiochemical properties- water solubility, chemical stability.
c) Pharmacokinetic properties- metabolic stability and toxicological aspects.
d) Chemical optimization potential- ease of chemical synthesis and derivatization.
The drug designing and discovery process include the following major steps:
- Drug Target Identification
- Target Validation
- Lead Compound Identification
- Lead Optimization
- Preclinical And Clinical development
- Administration of Drugs
- Absorption Of Drugs
- Drug Assays
- Preservation Of Pharma Product
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