In a metabolic pathway one or more enzymes have a greater effect on the rate of the all sequences, these regulatory enzymes can be exhibit increased or decreased catalytic activity in response to certain signals, which allows the cell to meet the changing needs for energy and for biomolecules required in growth and repair. The activities of regulatory enzymes are modulated in a variety of ways. Allosteric enzymes function through reversible and non-covalent binding of regulatory compounds. Other enzymes are regulated by reversible covalent modification.
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