The stationary phase is a stage in the growth curve of microorganisms (or cells) where the rate of cell division equals the rate of cell death, resulting in no net increase or decrease in the population size.
Key characteristics of the Stationary Phase:
- Nutrient depletion: As the culture grows, nutrients in the environment become limited, and waste products may accumulate, affecting cell growth.
- Balance between division and death: The number of new cells being produced is equal to the number of cells dying, so the population size stabilizes.
- Stress responses: Cells may undergo metabolic changes to survive under stressful conditions. Some may form spores or enter a dormant state to withstand unfavorable conditions.
- Limited resources: The growth rate slows due to the exhaustion of nutrients or accumulation of toxic byproducts.
This phase is followed by the death phase, where the number of dying cells exceeds the number of dividing cells, leading to a decrease in population.