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Asked By :  Ankit
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Local anesthetics are vasoconstrictors and decrease the

Local anesthetics are vasoconstrictors and decrease the absorption of the drug by the blood.




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Actually, local anesthetics themselves are not vasoconstrictors. However, they can cause vasodilation (widening of blood vessels), which may increase the rate of absorption into the bloodstream. This rapid absorption can lead to an increase in the risk of systemic toxicity.

To counteract this effect, vasoconstrictors (like epinephrine or levonordefrin) are often added to local anesthetics. The vasoconstrictors help reduce blood flow to the injection site, which decreases the rate of absorption, prolongs the duration of action of the anesthetic, and reduces the risk of systemic toxicity. Additionally, the vasoconstriction helps to control bleeding during procedures.

In summary:

  • Local anesthetics generally cause vasodilation, which could increase systemic absorption.
  • Vasoconstrictors (added to anesthetics) reduce absorption and provide benefits like prolonged anesthesia and decreased bleeding.

Answered By

Ankit

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