Unilateral papillitis hyperemic disc edema

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as well as the ophthalmic and central retinal arteries, are	•

Optic neuritis (ON) is defined as acute inflammation of the optic nerve. When the inflammation involves the disc, it is termed as

Management
•
•	Erythrocyte sedimentation rate (ESR).
Elevated in arteritic AION, normal in NAION
•
		•
		•
•	Temporal artery biopsy - To rule out GCA	•
•	Temporal artery biopsy - To rule out GCA	Optic Neuritis and Multiple Sclerosis
•	In Arteritic AION, 1-2g I.V. methylprednisolone should be	Optic Neuritis and Multiple Sclerosis

Clinical features	•	Pulfrich's stereo phenomenon (beer barrel appearance of the

	•

The currently accepted management is with intravenous methylprednisolone sodium succinate 250 mg every 6 hours or 1

•	Sudden onset, moderate-severe loss of vision, which can be	gram every day for three days followed by oral prednisone (1 mg/

progressive for about 10-14 days which then stabilizes and begins to improve.

•		dexamethasone 200 mg every day for three days followed by oral
•
•		The aim of this treatment is for the purpose of accelerating visual
•	Decreased brightness sense.	recovery only and it does not affect visual outcome after one year.
•	Relative afferent pupillary defect in the involved eye.	The ONTT also determined that the use of oral prednisone in
•	Relative afferent pupillary defect in the involved eye.	routinely prescribed doses (1 mg/kg per day) alone for 14 days is
•	Visual field defects (could be of variable severity and type	contraindicated, and was associated with increased risk of
		reccurrence. Patients receiving this therapy had a higher rate of

		new attacks of ON in both the initially affected and fellow eye,
•
•	Uhtoff's sign (decreased vision with or without limb weakness	Treatment with intravenous methylprednisolone followed by oral
•	following increasing body temperatures i.e., a hot bath or	corticosteroid regimen also reduces the two-year risk of
		development of clinical MS, particularly in patients with
		demyelinating lesions on MRI of the brain at the time of episode
	Romberg's sign (patient falls when they close their eyes),

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