Apted fic eds mansons tropical diseases

Specific investigation should be done for detection of Argemone oil adulteration in edible oils.

Nitric acid test, 5ml oil is shaken with an equal volume of nitric acid. On standing, the acid layer turns yellow, orange yellow or crimson, depending upon the amount of Argemone oil. The test is sensitive to a concentration of more than 0.25%. It has a high false positive rate and a positive test must be confirmed.

All contaminated mustard oil excluded: Steps should be taken to prevent contamination of mustard crops with the weed, Argemone mexicana. Selective Cultivation of yellow seeded mustard with which neither black coloured Argemone seeds nor dark brown Argemone oil mixes well so that adulteration can easily be detected even with naked eye. A strict ban on the sale of unbranded and unpacked mustard oil. Education and motivation of farmers to cultivate yellow seeded mustard and to make them aware of the identity of Argemone plants. Which grow as weeds in mustard fields.

Government agencies involved in enforcing the provisions of the prevention of food adulteration act must be made accountable in the event of occurrence of such epidemics. This means exemplary punishments for unscrupulous traders.

Investigate the case thoroughly and manage accordingly.

Summary

In case of epidemic dropsy increased total protein content of the aqueous humor of the eye has been demonstrated. It has been observed that those consuming a protein rich diet tend to develop a relatively mild form of dropsy. In eye, the fundus changes and glaucoma occur independently. Glaucoma in epidemic dropsy is hyper secretary glaucoma. Epidemic dropsy glaucoma is non congestive in nature, sanguinarine causes increased formation of aqueous humor resulting in marked rise in intraocular pressure. The rise of Intraocular pressure tends to develop four to eight weeks after the onset of dropsy. Visual field defect in epidemic dropsy occurs independently of the rise of I.O.P. and more frequently in early stage of disease. Prostaglandin and histamine release may have significant role in it’s pathogenesis. On fundus examination there will be venous dilatation and tortuosity, superficial retinal haemorrhages and toxic vasculitis may be seen. Gonioscopy reveals open angle of anterior chamber. Glaucoma may need surgical intervention but generally responds to medical management. Fundus Fluorescein angiography shows dilatation and tortuosity of retinal veins, prominent vascular