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Carboxylic Acids and Derivatives Assignment Help

Introduction to Carboxylic Acids and Derivatives:

The carboxyl group (abbreviated -CO2H or -COOH) is one of the most widely occurring functional groups in chemistry as well as biochemistry. The carboxyl group of a large family of related compounds called Carboxylic Acid Derivatives. This group of compounds also contains a carbonyl group, but now there is an electronegative atom (oxygen, nitrogen, or a halogen) attached to the carbonyl carbon. This difference in structure leads to a major change in reactivity. The systematic IUPAC nomenclature for carboxylic acid derivatives is different for the various compounds which are in this vast category, but each is based upon the name of the carboxylic acid closest to the derivative in structure.

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Reactions of Carboxylic Acid Derivatives

  1. Reactions of Acyl Halides, Friedel-Crafts Acylation (review)

  2. Reactions of Acid Anhydrides,

  3. Reactions of Esters, Hydrolysis, Reduction, and with Grignard reagents

  4. Reactions of Amides, Hydrolysis and Reduction

  5. Reactions of Nitriles, Hydrolysis, Reduction, and with Grignard reagents

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