Risk assessment involves determination of the potential and anticipated adverse effects of the recombinant DNA research to the concerned workers, and of the products of such research on human health and the environment consequent to their accidental or deliberate release or as a result of their consumption.
a) Initial risk assessment- The initial risk assessment is made by the investigators on the basis of the risk group (RG) to which the organism, on which he proposes to conduct experiments, belongs.
b) Comprehensive risk assessment- It is done following the initial risk assessment. The level of containment appropriate for an experiment is decide on the basis of Comprehensive risk assessment: the containment level for the experiment may, in the end, be comparable to that of the RG of the agent, or it may be raised or lowered as a result of the Comprehensive risk assessment.
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