Nature has it own rule, the birth of new born marks the beginning for cycle of life. Firstly, they are small and innocent, their body is completely soft and spongy but once they grow up the texture of certain organs completely changes. Skin that was once soft, becomes hard and tough, along with that some new development is seen. Then slowly when they start growing old, skin becomes loosened up and wrinkles are present all over the body along with declining function.
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Ageing is the natural process where the weakening of organs and tissues takes place thus resulting in death.
Though ageing is a natural process, but we can notice that some people get old fast and others do not. To find out the cause behind this, it is important to look over some of the reasons that results in ageing. The reasons are well described below:
One of the well- studied examples of aging can be seen in case of C.elegans. The life stage of C.elegans includes larval stages before becoming an adult. Even in the larval stages there are certain steps that need to be crossed; daurer stage is one of them. At this stage, C.elegans has the chance to decide when they want to enter the adult stage because they can stay in this stage for maximum of 6 months. At this stage no development in the body of C. elegans is seen and protection against ROS is at high level. So, if the genes that are involved in developmental pathway are mutated then, C.elegans can soon enter the adult stage and live longer because at that period of time, the genes for ROS protection are still active. Hence, mutation in some gene can increase the life span of the adult. The other process is the inhibition of genes in the germ line because germ cell decreases the longitivity whereas somatic cell increases the longitivity. Therefore, the alteration in gene can help to reduce C.elegans ageing.
In case of human, there are many more factors that are responsible for fast ageing process. This includes: smoking, drinking, stress, diseases, unhealthy lifestyle, irregular fooding habit etc. So, if all these factors are accounted for than the process of ageing can be slowed down. Image Reference: http://commons.wikimedia.org/wiki/File:Ageing_of_the_human_face.jpg